Invention Grant
US07645451B2 Human dickkopf-related protein and nucleic acid molecules and uses therefor
有权
人类dickkopf相关蛋白和核酸分子及其用途
- Patent Title: Human dickkopf-related protein and nucleic acid molecules and uses therefor
- Patent Title (中): 人类dickkopf相关蛋白和核酸分子及其用途
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Application No.: US11069137Application Date: 2005-02-28
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Publication No.: US07645451B2Publication Date: 2010-01-12
- Inventor: Sean A. McCarthy
- Applicant: Sean A. McCarthy
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McDermott, Will & Emery LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/18 ; C07K16/46

Abstract:
Novel Dkk and Dkk-related polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Dkk and Dkk-related proteins, the invention further provides isolated fusion proteins, antigenic peptides and antibodies. The invention also provides Dkk and Dkk-related nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and n which a Dkk and Dkk-related gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Public/Granted literature
- US20060294605A1 Novel human dickkopf-related protein and nucleic acid molecules and uses therefor Public/Granted day:2006-12-28
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