One embodiment of the invention provides a method for optimizing a variety of aspects of pipeline operations by using a genetic algorithm. Generally, the genetic algorithm is used to evolve a population of feasible solutions over successive generations until a termination condition is satisfied. Each solution specifies a feasible operational state of the pipeline system. Over successive generations existing solutions are modified, and an identified solution in the population is removed at each successive generation. Over repeated generations, the solutions in the population improve. Once an optimized production solution is generated, an optimized pressure solution may be generated using a direct pressure optimization process.