Invention Grant
- Patent Title: Methods for monitoring drug activities in vivo
- Patent Title (中): 体内监测药物活性的方法
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Application No.: US10793032Application Date: 2004-03-05
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Publication No.: US07643943B2Publication Date: 2010-01-05
- Inventor: Michael E. Burczynski , Joseph Boni , Andrew J. Dorner , Natalie C. Twine , Jennifer Stover , William L. Trepicchio , Virginia Fitzpatrick , Fred Immermann
- Applicant: Michael E. Burczynski , Joseph Boni , Andrew J. Dorner , Natalie C. Twine , Jennifer Stover , William L. Trepicchio , Virginia Fitzpatrick , Fred Immermann
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Joseph E. Zahner
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
Methods, systems and equipment useful for monitoring in vivo activities of CCI-779 or other drugs. Numerous drug activity genes can be identified by the present invention. The expression profiles of these genes in peripheral blood mononuclear cells are modulatable by CCI-779 or other drugs. Therefore, these genes can be used as surrogate markers for detecting or monitoring drug activities in vivo.
Public/Granted literature
- US20040235020A1 Methods for monitoring drug activities in vivo Public/Granted day:2004-11-25
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