Invention Grant
- Patent Title: siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)
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Application No.: US12157137Application Date: 2008-06-06
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Publication No.: US07642349B2Publication Date: 2010-01-05
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TAF1.
Public/Granted literature
- US20090082556A1 siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1) Public/Granted day:2009-03-26
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