Invention Grant
- Patent Title: Drugs for chronic pain
- Patent Title (中): 药物用于慢性疼痛
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Application No.: US10537439Application Date: 2003-12-03
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Publication No.: US07642289B2Publication Date: 2010-01-05
- Inventor: Ennio Ongini , Nicoletta Almirante , Piero Del Soldata
- Applicant: Ennio Ongini , Nicoletta Almirante , Piero Del Soldata
- Applicant Address: FR Sophia Antipolis - Valbonne
- Assignee: Nicox S.A.
- Current Assignee: Nicox S.A.
- Current Assignee Address: FR Sophia Antipolis - Valbonne
- Agency: Arent Fox LLP
- Priority: ITMI2002A2658 20021217
- International Application: PCT/EP03/50932 WO 20031203
- International Announcement: WO2004/054965 WO 20040701
- Main IPC: A61K31/16
- IPC: A61K31/16 ; A61K31/166 ; C07C229/04 ; C07C229/28

Abstract:
The present invention relates to nitrooxyderivatives or salts thereof having the following general formula (I): R—NR1c—(K)k0—(B)b0—(C)c0—NO2 (I) wherein c0, b0 and k0 are 0 or 1; R is the radical of an analgesic drug for chronic pain, for instance neurophatic pain; R1c is H or alkyl with from 1 to 5 carbon atoms; B is such that its precursor is selected from amino acids, hydroxy acids, polyalcohol, compounds; C is a bivalent radical containing an aliphatic, heterocyclic or aromatic radical.
Public/Granted literature
- US20060270608A1 Drugs for chronic pain Public/Granted day:2006-11-30
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