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US07642266B2 Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors 失效
取代的吡唑并[1,5-a]嘧啶作为蛋白激酶抑制剂

Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
Abstract:
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a] pyrimidine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions. An illustrative compound is shown below:
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