Invention Grant
US07642266B2 Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
失效
取代的吡唑并[1,5-a]嘧啶作为蛋白激酶抑制剂
- Patent Title: Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
- Patent Title (中): 取代的吡唑并[1,5-a]嘧啶作为蛋白激酶抑制剂
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Application No.: US11542852Application Date: 2006-10-04
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Publication No.: US07642266B2Publication Date: 2010-01-05
- Inventor: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer
- Applicant: Timothy J. Guzi , Kamil Paruch , Michael P. Dwyer
- Applicant Address: US NJ Kenilworth
- Assignee: Schering Corporation
- Current Assignee: Schering Corporation
- Current Assignee Address: US NJ Kenilworth
- Agent Palaiyur S. Kalyanaraman
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P35/04
![Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors](/abs-image/US/2010/01/05/US07642266B2/abs.jpg.150x150.jpg)
Abstract:
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a] pyrimidine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions. An illustrative compound is shown below:
Public/Granted literature
- US20070082901A1 Pyrazolopyrimidines as protein kinase inhibitors Public/Granted day:2007-04-12
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