Invention Grant
US07642248B2 Devices and processes for distribution of genetic material to mammalian limb
有权
将遗传物质分配给哺乳动物肢体的装置和方法
- Patent Title: Devices and processes for distribution of genetic material to mammalian limb
- Patent Title (中): 将遗传物质分配给哺乳动物肢体的装置和方法
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Application No.: US11694140Application Date: 2007-03-30
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Publication No.: US07642248B2Publication Date: 2010-01-05
- Inventor: Vladimir G. Budker , Jon A. Wolff
- Applicant: Vladimir G. Budker , Jon A. Wolff
- Applicant Address: US WI Madison
- Assignee: Roche Madison Inc
- Current Assignee: Roche Madison Inc
- Current Assignee Address: US WI Madison
- Agent Kirk Ekena; Mark Johnson
- Main IPC: A61K31/70
- IPC: A61K31/70
Abstract:
A process is described for the delivery of a therapeutic polynucleotide to limb muscle tissue suffering from or potentially suffering from Muscular Dystrophy. The polynucleotide is inserted into a mammalian limb vessel such as an artery. Delivery efficiency and distribution is enhanced by combining injection of a solution containing the polynucleotide with the use of an externally applied cuff.
Public/Granted literature
- US20070244067A1 DEVICES AND PROCESSES FOR DISTRIBUTION OF GENETIC MATERIAL TO MAMMALIAN LIMB Public/Granted day:2007-10-18
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