Invention Grant
- Patent Title: Bioconjugates comprising sulfated polysaccharides and their uses
- Patent Title (中): 包含硫酸化多糖的生物共轭物及其用途
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Application No.: US11649844Application Date: 2007-01-05
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Publication No.: US07642240B2Publication Date: 2010-01-05
- Inventor: Smader Cohen , Inbar Freeman
- Applicant: Smader Cohen , Inbar Freeman
- Applicant Address: IL Beer Sheva
- Assignee: Ben-Gurion University of the Negev Research and Development Authority
- Current Assignee: Ben-Gurion University of the Negev Research and Development Authority
- Current Assignee Address: IL Beer Sheva
- Agency: Browdy and Neimark, PLLC
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/00
Abstract:
The present invention provides bioconjugates comprising a sulfated polysaccharide such as alginate sulfate and hyaluronan sulfate and at least one bioactive polypeptide capable of binding a sulfate group of said sulfated polysaccharide. The bioactive polypeptide can be a heparin-binding polypeptide and/or a positively-charged polypeptide. Also, provided are delivery systems and methods for sustained release of said bioactive polypeptide(s) using said bioconjugates.
Public/Granted literature
- US20070110814A1 Bioconjugates comprising sulfated polysaccharides and their uses Public/Granted day:2007-05-17
Information query
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