Invention Grant
US07641691B2 Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
失效
生物降解/生物活性髓核植入物和治疗退化性椎间盘的方法
- Patent Title: Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
- Patent Title (中): 生物降解/生物活性髓核植入物和治疗退化性椎间盘的方法
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Application No.: US11505783Application Date: 2006-08-16
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Publication No.: US07641691B2Publication Date: 2010-01-05
- Inventor: Jeffrey C. Lotz , Olivier K. Colliou , David S. Bradford
- Applicant: Jeffrey C. Lotz , Olivier K. Colliou , David S. Bradford
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agent John P. O'Banion
- Main IPC: A61F2/44
- IPC: A61F2/44

Abstract:
A bioactive/biodegradable nucleus implant for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant is inflated with a high molecular weight fluid, gel or combination of fluid and elastomer, preferably an under-hydrated HA hydrogel/growth factor mixture with or without host cells. The implant includes an internal, integral, self-sealing valve that allows one-way filling of the implant after it is placed within the disc, and is made from a material that allows fibrous in growth thereby stabilizing the implant. A variety of substances can be incorporated into the implant to promote healing, prevent infection, or arrest pain.
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