The drainage catheter hub includes a locking cam for securing a suture to maintain an anchor configuration of the distal end of the drainage catheter. The locking cam is rotatable to a first position for securing the suture and a second position for releasing the suture. The locking cam includes a tapered surface which includes a release portion and a securement portion. The release portion allows movement of the suture while the securement portion cooperatively engages the suture in connection with the seat to minimize movement of the suture.