A method is disclosed for determining a position of a first image region in an image corresponding to a second image region in the image. The method comprises: providing the first image region comprising a reference position; providing the image; determining a plurality of signature values for different image positions in the first image region; assigning relative offsets of a plurality of image positions in the first image region to respectively determined signature values; determining a plurality of correspondence signature values to different image positions in the image; determining relative offsets relative to determined correspondence signature values with use of the assignment; calculating target positions by summing the relative offset and corresponding image position; incrementally assigning a weighting value to a calculated target position, thus forming an incremental weighting value; and determining the position of the first image region by finding an extremum in the incremental weighting values.