Invention Grant
- Patent Title: EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions
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Application No.: US15569407Application Date: 2016-04-26
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Publication No.: US12023348B2Publication Date: 2024-07-02
- Inventor: Ofer Sarig , Eli Sprecher
- Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
- Applicant Address: IL Tel-Aviv
- Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
- Current Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
- Current Assignee Address: IL Tel-Aviv
- International Application: PCT/IL2016/050439 2016.04.26
- International Announcement: WO2016/174674A 2016.11.03
- Date entered country: 2017-10-26
- Main IPC: A61K31/704
- IPC: A61K31/704 ; A61K31/122 ; A61K31/137 ; A61K31/167 ; A61K31/277 ; A61K31/365 ; A61K31/366 ; A61K31/37 ; A61K31/404 ; A61K31/423 ; A61K31/427 ; A61K31/433 ; A61K31/4402 ; A61K31/4453 ; A61K31/4535 ; A61K31/454 ; A61K31/4738 ; A61K31/4741 ; A61K31/4745 ; A61K31/475 ; A61K31/498 ; A61K31/53 ; A61K31/538 ; A61K31/5415 ; A61K31/566 ; A61K31/58 ; A61K31/688 ; A61K45/06 ; A61P17/00 ; A61P17/06

Abstract:
A method of treating an inflammation or a hyperproliferative disease in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of a compound selected from the group consisting of:
a compound represented by Formula I:
or a pharmaceutically acceptable salt thereof,
a compound represented by Formula II:
and a compound represented by Formula III:
wherein the variables in Formulae I, II and III are as defined in the specification.
a compound represented by Formula I:
or a pharmaceutically acceptable salt thereof,
a compound represented by Formula II:
and a compound represented by Formula III:
wherein the variables in Formulae I, II and III are as defined in the specification.
Public/Granted literature
- US20180289728A1 EGR1 TARGETING MOLECULES FOR THE TREATMENT OF INFLAMMATORY AND HYPERPROLIFERATIVE CONDITIONS Public/Granted day:2018-10-11
Information query
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