Invention Grant
- Patent Title: IgG bispecific antibodies and processes for preparation
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Application No.: US16932215Application Date: 2020-07-17
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Publication No.: US11976136B2Publication Date: 2024-05-07
- Inventor: Hector Aldaz , Shane Krummen Atwell , Stephen John Demarest , Karen Jean Froning , Brian Arthur Kuhlman , Andrew Philip Leaver-Fay
- Applicant: Eli Lilly and Company , The University of North Carolina at Chapel Hill
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company,The University of North Carolina at Chapel Hill
- Current Assignee: Eli Lilly and Company,The University of North Carolina at Chapel Hill
- Current Assignee Address: US IN Indianapolis; US NC Chapel Hill
- Agency: Nielsen IP Law LLC
- The original application number of the division: US15545047
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C07K16/00 ; C07K16/28 ; C07K16/32
Abstract:
The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (CH3/CH3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.
Public/Granted literature
- US20210054103A1 IgG Bispecific Antibodies and Processes for Preparation Public/Granted day:2021-02-25
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