Invention Grant
- Patent Title: Transgene cassettes, AAV vectors, and AAV viral vectors for expression of human codon-optimized CSTB
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Application No.: US17387035Application Date: 2021-07-28
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Publication No.: US11946065B2Publication Date: 2024-04-02
- Inventor: Berge A. Minassian , Emrah Gumusgoz
- Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: DLA Piper LLP US
- Main IPC: C12N15/864
- IPC: C12N15/864 ; C12N7/00 ; C12N15/11 ; C12N15/113 ; C12N15/15 ; C12N15/86
Abstract:
The present disclosure provides methods and compositions for the treatment of diseases and genetic disorders linked to CSTB loss and/or misfunction. The methods and compositions of the present disclosure include rAAV vectors and rAAV viral vectors comprising transgene nucleic acid molecules encoding CSTB polypeptides.
Information query
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