Systems and methods for characterizing a camera system on a mobile device are disclosed. Characterization of the camera system may be implemented by providing a diffraction pattern of dots at controlled, defined angles to the camera system. Images of the diffraction pattern may be captured during a focus sweep through predetermined focus positions and/or while changing the relative locations between the lens and image sensor at the predetermined focus positions. The captured images may be analyzed to determine calibration data that provides physical measurement of properties of the camera system. The calibration data may then be implemented by the camera system to produce enhanced imaging on the mobile device.