A removable maintenance fluid holder for a digital dispense system, a digital dispense system containing the removable maintenance fluid holder, and a method of maintaining a fluid droplet dispense cartridge. The removable maintenance fluid holder includes a housing having a handle end and a fluid receptacle end distal from the handle end. The fluid receptable end includes a fluid receptacle for holding fluid dispensed from a fluid droplet ejection head of a fluid droplet cartridge in the digital dispense system. The removable maintenance fluid holder is configured to be inserted and removed from the digital dispense system on a periodic basis.