Invention Grant
- Patent Title: Compositions and methods for the treatment of Lowe syndrome
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Application No.: US17370676Application Date: 2021-07-08
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Publication No.: US11857549B2Publication Date: 2024-01-02
- Inventor: Ruben Claudio Aguilar
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Purdue Research Foundation
- Main IPC: C07D498/18
- IPC: C07D498/18 ; A61K31/436 ; A61K31/505 ; A61P3/00

Abstract:
A combination of active agents for the treatment of Lowe Syndrome (LS) comprising a RhoA inhibitor and a mTOR inhibitor; a pharmaceutical composition comprising the combination and a pharmaceutically acceptable carrier; a combination of pharmaceutical compositions in which one composition comprises a RhoA inhibitor and the other composition comprises a mTOR inhibitor; and a method of treating a patient for LS.
Public/Granted literature
- US20220079941A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LOWE SYNDROME Public/Granted day:2022-03-17
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