An article of footwear includes an upper and an adjustable lacing system. The adjustable lacing system includes a plurality of fastener engaging elements located at the medial and lateral sides of the upper, where at least one of the medial side and the lateral side includes sets of fastener engaging elements. Each set of fastener engaging elements is distanced from another set in a direction transverse a lengthwise direction of the upper, and the fastener engaging elements are configured to engage with and retain a fastener structure that extends between the medial and lateral sides of the upper such that the fastener structure can be selectively engaged with different sets of fastener engaging elements to adjust a fit of the upper around a width of the foot disposed within the cavity.