Systems and methods are disclosed herein that relate to Peak-to-Average Power Ratio (PAPR) reduction in a MIMO OFDM transmitter system. In some embodiments, a method of operation of a transmitter system includes, for each carrier of two or more carriers, performing precoding of frequency-domain input signals for the carrier to provide frequency-domain precoded signals for the carrier, the frequency-domain input signals for the carrier being for a plurality of transmit layers for the carrier, respectively. The method further includes processing the two or more pluralities of frequency-domain precoded signals for the two or more carriers, respectively, in accordance with a multi-carrier processing scheme to provide a plurality of multi-carrier time-domain transmit signals for a plurality of antenna branches, respectively, of the MIMO OFDM transmitter system. The multi-carrier processing scheme provides PAPR reduction for Cyclic Prefixes (CPs) of the plurality of multi-carrier time-domain transmit signals for the plurality of antenna branches.