The present disclosure relates to a data drive circuit capable of increasing clock and data recovery stability by generating a clock synchronized with input data, a clock recovery method thereof, and a display drive device having the same, and the data drive circuit according to an aspect includes a receiver including a clock and data recovery part configured to recover a test data pattern from input data using an internal clock, and a data comparator configured to compare the recovered test data pattern with a predetermined reference data pattern to generate a control signal according to a degree of asynchronicity between the recovered test data pattern and the reference data pattern, wherein the clock and data recovery part recovers a clock synchronized with the input data according to the control signal, and recovers control information and image data from the input data using the recovered clock.