In a data processing system running at least one application on a hardware platform that includes at least one processor and a plurality of coprocessors, at least one kernel dispatched by an application is intercepted by an intermediate software layer running logically between the application and the system software. Compute functions are determined within kernel(s), and data dependencies are determined among the compute functions. The compute functions are dispatched to selected ones of the coprocessors based at least in part on the determined data dependencies and kernel results are returned to the application that dispatched the respective kernel.