The present invention relates to a technical field of user interface display, and in particular to a method, system, and device for adaptive configuration of a user interface, and a medium. The method of the present invention includes: respectively making a correspondence between one or more user interface components and one area of a plurality of areas of a panel; performing a stretching operation on the plurality of areas and the one or more user interface components, and performing a moving operation on the plurality of areas, to generate an adaptive panel and one or more adaptive user interface components adapted to user equipment; and respectively placing the one or more adaptive user interface components in corresponding areas of the adaptive panel to generate an adaptive user interface. The present invention simplifies design steps of user interface, enhances operability, and implements adaptive configuration of the user interface.