Invention Grant
- Patent Title: Endodermal cell population, and method for producing cell population of any of three germ layers from pluripotent cell
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Application No.: US16481418Application Date: 2018-01-26
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Publication No.: US11746331B2Publication Date: 2023-09-05
- Inventor: Masato Ibuki , Hitoshi Okochi , Shigeharu Yabe
- Applicant: KANEKA CORPORATION , NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE
- Applicant Address: JP Osaka
- Assignee: NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE
- Current Assignee: NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE
- Current Assignee Address: ; JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP 17012802 2017.01.27
- International Application: PCT/JP2018/002545 2018.01.26
- International Announcement: WO2018/139600A 2018.08.02
- Date entered country: 2019-07-26
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
An object of the present invention is to provide an endodermal cell population for obtaining optimal somatic cells as cell therapy preparations. The endodermal cell population of the present invention has a reduced content proportion of undifferentiated cells in the cell population and contains endodermal cells differentiable into optimal somatic cells as cell therapy preparations. Further, a somatic cell derived from the endodermal cell population of the present invention has excellent therapeutic effects as a cell therapy preparation.
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