Invention Grant
- Patent Title: Method for producing optically active pyrrolidine compounds
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Application No.: US17344152Application Date: 2021-06-10
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Publication No.: US11746099B2Publication Date: 2023-09-05
- Inventor: Takao Teshima , Takafumi Yamagami , Tetsuo Yamaguchi , Junki Ando
- Applicant: MITSUBISHI TANABE PHARMA CORPORATION
- Applicant Address: JP Osaka
- Assignee: MITSUBISHI TANABE PHARMA CORPORATION
- Current Assignee: MITSUBISHI TANABE PHARMA CORPORATION
- Current Assignee Address: JP Osaka
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP 17014999 2017.01.31
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07B53/00 ; C07D207/09 ; C07D211/62

Abstract:
The present invention provides a process for preparing a compound represented by formula (VII), which comprises reacting a compound represented by formula (VI) with a malonic acid derivative in the presence of a base and an asymmetric catalyst in a two layer solvent system of hydrophobic solvent and water,
(wherein R2 and R3 each independently represents a protecting group for carboxyl group).
(wherein R2 and R3 each independently represents a protecting group for carboxyl group).
Public/Granted literature
- US20220119364A2 METHOD FOR PRODUCING OPTICALLY ACTIVE PYRROLIDINE COMPOUNDS Public/Granted day:2022-04-21
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