A method, a system and a computer program product may evaluate reduction of disease risk. Patient data of a patient may be received. A selection of a disease outcome may be received. A risk score that the patient will experience the selected disease outcome may be determined. The determining may use the patient data. Intervention options may be generated based on the patient data and by accessing a medical record data structure. An intervention effect for each of the intervention options may be determined. The intervention effect may change the risk score. The intervention effects may be compared. A recommendation of at least one of the intervention options may be provided based on the comparing of the intervention effects.