Various embodiments may provide systems and methods for managing transmit (TX) timing of data transmissions. The methods include applying a plurality of radio frequency (RF) channel factors related to data uplink transmissions by the wireless device to a TX timing model configured to provide as an output a TX timing for a data transmission to a base station and a number of carriers for sending the data transmission, and selecting a TX time and a number of carriers for sending a next data transmission to the base station based in part on the TX timing model output.