Methods, apparatus, and processor-readable storage media for automated issue detection and remediation across multiple user systems using healing-as-a-service techniques are provided herein. An example computer-implemented method includes obtaining system configuration data from at least a portion of multiple user systems within a network; obtaining an alert pertaining to an issue attributed to a first of the user systems; training a machine learning model related to user system issue detection using at least a portion of the system configuration data and data related to the alert; determining user system configuration adjustments related to remedying at least a portion of the issue, by processing the data related to the alert using the trained machine learning model; automatically performing the user system configuration adjustments in connection with the first user system; and sharing, using at least one healing-as-a-service component, the trained machine learning model with the user systems in the network.