Various implementations of fiber optic inspection tools with integrated cleaning mechanisms are disclosed. The fiber optic inspection and cleaning tool includes a housing, a cleaning system and an imaging system. The cleaning system includes a pay-off reel, a take-up reel, a spindle and a cleaning tape that travels off the pay-off reel, around the spindle, and onto the take-up reel. The imaging system includes a camera and a light source. The camera, spindle, and cleaning tape are aligned along a visual axis. The pay-off reel, take-up reel, camera and light source are all located within the housing.