Invention Grant
- Patent Title: CD8+T-cell subsets as markers for prediction of delayed fracture healing
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Application No.: US16711480Application Date: 2019-12-12
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Publication No.: US11639935B2Publication Date: 2023-05-02
- Inventor: Georg Duda , Hans-Dieter Volk , Simon Reinke , Christian Meisel , Christian Kleber , Sven Geissler , Katharina Schmidt-Bleek
- Applicant: Charite Universitätsmedizin Berlin
- Applicant Address: DE Berlin
- Assignee: Charite Universitätsmedizin Berlin
- Current Assignee: Charite Universitätsmedizin Berlin
- Current Assignee Address: DE Berlin
- Agency: JMB Davis Ben-David
- Priority: EP12153850 20120203
- Main IPC: G01N33/569
- IPC: G01N33/569 ; A61K31/00 ; A61K39/395
Abstract:
The present invention relates to a method for diagnosis of delayed bone fracture healing, comprising determining the frequency of a subpopulation of CD8+ cells selected from a first group comprised of CD8+CD57+, CD8+CD28− and CD8+CD28−/CD57+, in a sample obtained from a subject. The present invention further relates to a system and a kit of parts for prediction and resulting options for preventing of delayed bone fracture healing.
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