A refrigerator appliance includes a chilled chamber defining a plurality of cooling zones and a lighting assembly comprising a plurality of lighting zones corresponding to the plurality of cooling zones. A climate control system generates and selectively directs a flow of cooling air into the plurality of cooling zones such that the temperature in each zone is independently regulated and the lighting assembly selectively illuminates the plurality of lighting zones to provide user feedback regarding the operation of the climate control system, e.g., by indicating which zones are receiving the flow of cooling air, by notifying a user when a zone has reached a setpoint temperature, or by identifying the presence and location of a flow restriction.