A user equipment (UE) includes a first communication component configured to use a first frequency band, such as ultra-wide band (UWB), and a second communication component configured to use an intermediate frequency (IF) band that overlaps with the UWB band, such as an IF millimeter wave (mmWave) band. The second communication component conducts an IF signal along an internal signal conduction line that may interfere with UWB processing. A processor of the UE is configured to detect an indication of such interference, and, in response to the indication of interference, control the second communication component to adjust a characteristic of the IF band signal to mitigate the interference, such as by reducing its signal strength. The amount by which the IF band signal strength is reduced may be controlled to achieve a desired tradeoff between various performance metrics, such as power consumption and quality of service.