Methods and computer systems are provided for issuing or suppressing patient alerts prior to order entry. In some embodiments, alert information is provided prior to a user placing an order, based on proactive clinical checking prior to ordering, thereby avoiding the need to change or cancel orders later. In some cases, proactive clinical checking uses data regarding physicians or other medical professionals, and/or patients, to determine whether or not an alert should be issued that requires a user to accept or override an alert. In embodiments, alert information may still be displayed but, based on dynamic rules, the alert may not require a response from a user. The providing of alerts prior to ordering, or the suppressing of alerts based on data, can address alert fatigue by users and improve patient care.