The present invention provides an in-vehicle image pickup device wherein highly accurate optical axis adjustment of an image pickup unit with respect to a housing can be performed, while suppressing precision machining of the housing as much as possible. The present invention is provided with: camera modules having a lens holder, which has the optical axis of a lens as a normal line, and which has one or more reference surfaces that are formed therein; and a housing having an insertion hole, into which the lens holder is inserted, facing surfaces facing the reference surfaces, and adhesive filling sections penetrating from the side of the facing surfaces to the reverse side of the facing surfaces.