Invention Grant
- Patent Title: Polynucleotide enrichment and amplification using CRISPR-Cas or Argonaute systems
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Application No.: US16099953Application Date: 2017-05-10
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Publication No.: US11542544B2Publication Date: 2023-01-03
- Inventor: Jeffrey G. Mandell , Molly He
- Applicant: Illumina, Inc.
- Applicant Address: US CA San Diego
- Assignee: Illumina, Inc.
- Current Assignee: Illumina, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Knobbe, Martens, Olson & Bear, LLP
- International Application: PCT/US2017/032021 WO 20170510
- International Announcement: WO2017/197027 WO 20171116
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6844 ; C12Q1/686
Abstract:
A method for enriching or amplifying a target nucleic acid including providing a system having a guide nucleic acid, and a Cas or Argonaute protein or a variant thereof. The guide nucleic acid contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid, and contacting the target nucleic acid with the system to form a complex.
Public/Granted literature
- US20190136303A1 POLYNUCLEOTIDE ENRICHMENT AND AMPLIFICATION USING CRISPR-CAS OR ARGONAUTE SYSTEMS Public/Granted day:2019-05-09
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