Invention Grant
- Patent Title: TRIM11 for degradation of protein aggregates
-
Application No.: US15577915Application Date: 2016-05-27
-
Publication No.: US11542500B2Publication Date: 2023-01-03
- Inventor: Xiaolu Yang , Lili Guo
- Applicant: The Trustees of the University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Riverside Law LLP
- International Application: PCT/US2016/034751 WO 20160527
- International Announcement: WO2016/196328 WO 20161208
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/113 ; A61K38/17 ; G01N33/50 ; G01N33/68 ; A61P11/12 ; A61P25/28 ; C12N7/00
Abstract:
The present invention relates to compositions and methods for promoting the degradation of misfolded proteins and protein aggregates. The compositions and methods may be used to treat a disorder associated with misfolded proteins or protein aggregates. In certain instances, the compositions and methods relate to modulators of one or more TRIM proteins or one or more STUbLs.
Public/Granted literature
- US20180163202A1 Compositions and Methods for Degradation of Misfolded Proteins Public/Granted day:2018-06-14
Information query
