Invention Grant
- Patent Title: 3D microphysiologic system
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Application No.: US16659520Application Date: 2019-10-21
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Publication No.: US11542475B2Publication Date: 2023-01-03
- Inventor: Teresa K. Woodruff , Ji-Yong Julie Kim , Joanna E. Burdette , Spiro Getsios , Sevim Yildiz Arslan , Shuo Xiao , Jie Zhu
- Applicant: Northwestern University , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Applicant Address: US IL Evanston; US IL Urbana
- Assignee: Northwestern University,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee: Northwestern University,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee Address: US IL Evanston; US IL Urbana
- Agency: Quarles & Brady LLP
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12M3/00 ; C12M3/06

Abstract:
The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
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