Invention Grant
- Patent Title: Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids
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Application No.: US16744118Application Date: 2020-01-15
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Publication No.: US11542229B2Publication Date: 2023-01-03
- Inventor: Daniel J. Siegwart , Jason B. Miller
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: C07C311/32
- IPC: C07C311/32 ; C12N15/88 ; C07F9/09 ; C07F9/10 ; C12N15/11 ; B82Y5/00 ; C07C229/06 ; A61K47/69 ; A61K47/54 ; A61K48/00 ; C07C309/14 ; C12N15/113
Abstract:
The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas: wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.
Information query
