A video conference system including a transmitter device and a receiver device is provided. The transmitter device includes a transmitter control unit, a transmitter input interface, a transmitter video circuit and a first wireless transmission module. The transmitter control unit is coupled to a video output port of an information system and receive a first video data from the video output port. The transmitter input interface receives a second video data from a first video source. The transmitter video circuit combines the first video data and the second video data as a combined video data. The first wireless transmission module transmits the combined video data to the receiver device. The receiver device, coupled to the display device, includes a second wireless transmission module, which receives the combined video data. The receiver device transmits the combined video data to the display device.