Techniques are provided for identifying interactions between natural medicines and modern medicines. A corpus of information is analyzed pertaining to interactions of natural medicines with modern medicines for treating a condition. A mapping is created, wherein natural medicines are mapped to modern medicines for treating the condition. An on-line clinical trial study group is created, allowing participation by users, wherein a participation in a group is allowed for a selected set of users based on a group medication usage profile. Information from participants in each group is collected, and the collected information is analyzed.