A system for managing an industrial workflow including a plurality of asset tags, each tag associated with a corresponding asset, and a plurality of point of interest reader nodes, each reader node including at least one BLE radio in communication with a subset of the plurality of asset tags and a communications manager in communication with at least one cloud server. The system further includes a cloud server having a location services module, a process and workflow editor configured to enable a user to access a plurality of rules in a process flow library regarding how different types of assets are expected to move through a facility, and a real-time compute engine configured to generate a sequence of events for an asset and interpret the process and workflow plan to determine whether a trigger event has occurred.