Invention Grant
- Patent Title: Compositions and methods of manufacturing trivalent filovirus vaccines
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Application No.: US16879668Application Date: 2020-05-20
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Publication No.: US11433129B2Publication Date: 2022-09-06
- Inventor: Oreola Donini , Axel Lehrer
- Applicant: Soligenix, Inc. , University of Hawaii
- Applicant Address: US NJ Princeton; US HI Honolulu
- Assignee: Soligenix, Inc.,University of Hawaii
- Current Assignee: Soligenix, Inc.,University of Hawaii
- Current Assignee Address: US NJ Princeton; US HI Honolulu
- Agency: Lewis Kohn & Walker LLP
- Agent David M. Kohn
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N7/00 ; A61K39/39 ; A61P31/14 ; A61K39/00

Abstract:
Disclosed is a stable immunogenic composition capable of eliciting a robust and durable immune response, comprising at least one antigen consisting of a filovirus glycoprotein and at least one nano-emulsion adjuvant which are co-lyophilized and can be reconstituted immediately prior to use. Also disclosed is a vaccine composition comprising at least two antigens, wherein each antigen is specific to a different genus of filovirus and which also comprises at least one nano-emulsion adjuvant.
Public/Granted literature
- US20200376109A1 Compositions and Methods of Manufacturing Trivalent Filovirus Vaccines Public/Granted day:2020-12-03
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