A cartridge for ligating clips includes compartments formed of partitions lying in spaced parallel planes and a stringer spanning between the partitions. The legs of a clip are joined at a hinge which is seated over the stringer. The stringer comprises a substantially cylindrical body and a depending narrow support flange. Opposed faces of adjacent partitions include areas of reduced thickness spaced apart a distance sufficient to permit limited pivotal movement of the clip about the stringer. An abutment edge of the partition face provides a stop which is engaged by bosses at the ends of the clip legs to limit pivotal movement of the clip legs and prevent ribs of the clip from engaging the stringer.