Invention Grant
- Patent Title: Determining potential cancer therapeutic targets by joint modeling of survival events
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Application No.: US16011231Application Date: 2018-06-18
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Publication No.: US11410745B2Publication Date: 2022-08-09
- Inventor: Zhaonan Sun , Zach Shahn , Ping Zhang , Fei Wang , Jianying Hu
- Applicant: International Business Machines Corporation
- Applicant Address: US NY Armonk
- Assignee: International Business Machines Corporation
- Current Assignee: International Business Machines Corporation
- Current Assignee Address: US NY Armonk
- Agency: Amin, Turocy & Watson, LLP
- Main IPC: G16B5/00
- IPC: G16B5/00 ; G16H10/60 ; G16H50/30 ; G16B10/00 ; G16B20/00

Abstract:
Techniques are described that facilitate determining potential cancer gene therapy targets by joint modeling of cancer survival events. In one embodiment, a computer-implemented comprises employing, by a device operatively coupled to a processor, a multi-task learning model to determine active genetic factors respectively associated with different types of cancer based on cancer survival data and patient genomic data for groups of patients that respectively survived the different types of cancer. The computer-implemented method further comprises, determining, by the device, common active genetic factors of the active genetic factors that are shared between two or more types of cancer of the different types of cancer.
Public/Granted literature
- US20190384889A1 DETERMINING POTENTIAL CANCER THERAPEUTIC TARGETS BY JOINT MODELING OF SURVIVAL EVENTS Public/Granted day:2019-12-19
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