Invention Grant
- Patent Title: Formulations for drying bacterial cell extracts
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Application No.: US16841307Application Date: 2020-04-06
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Publication No.: US11408021B2Publication Date: 2022-08-09
- Inventor: Martin Chandler , Kirk Hayenga , Henry Heinsohn
- Applicant: Sutro Biopharma, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Sutro Biopharma, Inc.
- Current Assignee: Sutro Biopharma, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12P1/04 ; C12P21/02 ; C07K14/535 ; C07K16/00
Abstract:
This invention provides for an improved method of stabilizing freeze dried bacterial extracts with a carbohydrate lyoprotectant such that the extracts can be for use in cell free protein synthesis. Also provided herein are formulations for stable, freeze dried bacterial extracts that when stored at room temperature retain at least about 70% protein synthesis activity compared to undried frozen bacterial extracts.
Public/Granted literature
- US20200299745A1 FORMULATIONS FOR DRYING BACTERIAL CELL EXTRACTS Public/Granted day:2020-09-24
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