Invention Grant
- Patent Title: Screening method for pain suppressor and pharmaceutical composition for prevention or treatment of pain
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Application No.: US16802258Application Date: 2020-02-26
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Publication No.: US11407826B2Publication Date: 2022-08-09
- Inventor: Toshihide Yamashita , Yasufumi Hayano , Moe Yamada
- Applicant: Osaka University
- Applicant Address: JP Osaka
- Assignee: Osaka University
- Current Assignee: Osaka University
- Current Assignee Address: JP Osaka
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: JP2015-025954 20150213
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K38/00 ; A61K39/395 ; C12N15/113 ; G01N33/50 ; A61K39/00 ; A61K45/00 ; C12Q1/6883

Abstract:
The present invention provides a screening method for a pain suppressor, which method comprises using FLRT3 to select a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord. In addition, the present invention provides a pharmaceutical composition for prevention or treatment of pain, which pharmaceutical composition comprises, as an active ingredient, a substance capable of inhibiting FLRT3 expression or a substance capable of inhibiting FLRT3 transport to the spinal cord.
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