Invention Grant
- Patent Title: Substituted piperidines as kinase inhibitors
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Application No.: US16770213Application Date: 2018-12-28
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Publication No.: US11407754B2Publication Date: 2022-08-09
- Inventor: In Woo Kim , Nam Youn Kim , Seung Hwarn Jeong , Bo-Kyoung Kim , Jun Hee Lee
- Applicant: Daewoong Pharmaceutical Co., Ltd.
- Applicant Address: KR Gyeonggi-do
- Assignee: Daewoong Pharmaceutical Co., Ltd.
- Current Assignee: Daewoong Pharmaceutical Co., Ltd.
- Current Assignee Address: KR Gyeonggi-do
- Agency: Marshall, Gerstein & Borun LLP
- Priority: KR10-2017-0183062 20171228
- International Application: PCT/KR2018/016813 WO 20181228
- International Announcement: WO2019/132561 WO 20190704
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04

Abstract:
The present invention relates to a compound represented by the following Chemical Formula 1, or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof, and the compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions: wherein, X1 is —NR1—, —O—, or —S—, X2 is CH or N, R1 is C1-5 alkyl, C3-6 cycloalkyl, CH2CHF2, or CH2CF3, wherein the C1-5 alkyl is optionally substituted with one NHC(O)OC(CH3)3 substituent, R2 is H, C1-5 alkyl, or halogen, and R3 is H or C1-5 alkyl.
Public/Granted literature
- US20210188854A1 Amino-methyl Piperidine Derivative as Kinase Inhibitor Public/Granted day:2021-06-24
Information query
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