Invention Grant
- Patent Title: Substituted indoline derivatives as dengue viral replication inhibitors
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Application No.: US16612670Application Date: 2018-05-18
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Publication No.: US11407715B2Publication Date: 2022-08-09
- Inventor: Jean-François Bonfanti , Bart Rudolf Romanie Kesteleyn , Dorothée Alice Marie-Eve Bardiot , Arnaud Didier M Marchand , Erwin Coesemans , Jérôme Michel Claude Fortin , Guillaume Jean Maurice Mercey , Pierre Jean-Marie Bernard Raboisson
- Applicant: JANSSEN PHARMACEUTICALS, INC. , KATHOLIEKE UNIVERSITEIT LEUVEN
- Applicant Address: US NJ Titusville; BE Leuven
- Assignee: JANSSEN PHARMACEUTICALS, INC.,KATHOLIEKE UNIVERSITEIT LEUVEN
- Current Assignee: JANSSEN PHARMACEUTICALS, INC.,KATHOLIEKE UNIVERSITEIT LEUVEN
- Current Assignee Address: US NJ Titusville; BE Leuven
- Agency: Burns & Levinson, LLP
- Agent Shawn P. Foley; Chris Lorenc
- Priority: EP17172237 20170522
- International Application: PCT/EP2018/063028 WO 20180518
- International Announcement: WO2018/215315 WO 20181129
- Main IPC: C07D209/14
- IPC: C07D209/14 ; A61P31/14 ; A61K45/06
Abstract:
The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.
Public/Granted literature
- US20200255376A1 SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS Public/Granted day:2020-08-13
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