Invention Grant
- Patent Title: Human lymphoid tissue-on-chip
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Application No.: US16318591Application Date: 2017-07-18
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Publication No.: US11406975B2Publication Date: 2022-08-09
- Inventor: Girija Goyal , Donald E. Ingber
- Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Applicant Address: US MA Cambridge
- Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: US MA Cambridge
- Agency: Nixon Peabody LLP
- International Application: PCT/US2017/042657 WO 20170718
- International Announcement: WO2018/017605 WO 20180125
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12N5/0781 ; C12N5/0783 ; A61K35/28 ; A61P35/00 ; A61K35/17 ; C12M3/06 ; A61P37/04 ; C12M3/00 ; A61P7/00 ; C12N5/00 ; C12N5/0786 ; C12N5/078 ; C12N5/071 ; C12N5/09 ; G01N33/50
Abstract:
An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
Public/Granted literature
- US20190232277A1 HUMAN LYMPHOID TISSUE-ON-CHIP Public/Granted day:2019-08-01
Information query
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