Provided is a circulation pipeline (10) for intracavity hyperthermic perfusion, the circulation pipeline comprising a heating tank (100), a liquid intake pipeline (101), a liquid discharge pipeline (102), a circulating pump (200), a pre-filling pipeline (103), a liquid return pipeline (104), a cavity entry pipeline (105) and a cavity exit pipeline (106), wherein a liquid storage cavity (100a) is formed in the heating tank (100), and the liquid intake pipeline (101) is in communication with the liquid storage cavity (100a). A medicinal liquid enters the liquid storage cavity (100a) of the heating tank (100) through the liquid intake pipeline (101).