Invention Grant
- Patent Title: Materials and methods useful to induce cancer cell death via methuosis or autophagy or a combination thereof
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Application No.: US16650986Application Date: 2018-09-26
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Publication No.: US11406626B2Publication Date: 2022-08-09
- Inventor: Amit K. Tiwari , Chandrabose Karthikeyan , Haneen Amawi , Paul W. Erhardt , Piyush Trivedi
- Applicant: The University of Toledo
- Applicant Address: US OH Toledo
- Assignee: The University of Toledo
- Current Assignee: The University of Toledo
- Current Assignee Address: US OH Toledo
- Agency: MacMillan, Sobanski & Todd, LLC
- International Application: PCT/US2018/052809 WO 20180926
- International Announcement: WO2019/067511 WO 20190404
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/122 ; C07D401/14 ; C07D513/04

Abstract:
Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.
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